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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNB1
All Species:
30.3
Human Site:
Y191
Identified Species:
55.56
UniProt:
P14635
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14635
NP_114172.1
433
48337
Y191
E
Q
A
V
R
P
K
Y
L
L
G
R
E
V
T
Chimpanzee
Pan troglodytes
XP_517728
536
59103
Y294
E
Q
A
V
R
P
K
Y
L
L
G
R
E
V
T
Rhesus Macaque
Macaca mulatta
XP_001091533
433
48375
Y191
E
Q
A
V
R
P
K
Y
L
L
G
R
E
V
T
Dog
Lupus familis
XP_850398
425
47378
Y183
E
Q
A
V
K
P
K
Y
L
L
G
R
E
V
T
Cat
Felis silvestris
Mouse
Mus musculus
P24860
430
48033
Y188
E
Q
S
V
R
P
K
Y
L
Q
G
R
E
V
T
Rat
Rattus norvegicus
P30277
423
47373
Y181
E
Q
S
V
R
P
K
Y
L
L
G
R
E
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507609
428
47366
Y186
E
Q
A
V
R
P
K
Y
L
V
G
Q
E
V
T
Chicken
Gallus gallus
P29332
399
44633
T164
P
H
Y
L
D
G
K
T
I
N
G
R
M
R
A
Frog
Xenopus laevis
P13350
397
44655
G165
L
H
G
Q
E
V
T
G
N
M
R
A
I
L
I
Zebra Danio
Brachydanio rerio
NP_571588
398
44818
N167
A
G
K
E
V
T
G
N
M
R
A
I
L
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20439
530
59237
H278
E
Q
P
I
H
K
D
H
L
A
G
Q
K
E
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39071
444
50417
Y201
E
Q
R
P
S
T
S
Y
M
V
Q
V
Q
R
D
Baker's Yeast
Sacchar. cerevisiae
P24869
491
56228
D250
I
T
L
P
K
K
E
D
L
Y
Q
H
R
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.5
98.6
91.2
N.A.
86.3
84.7
N.A.
75.7
50.5
66.2
61.8
N.A.
34.3
N.A.
N.A.
N.A.
Protein Similarity:
100
80.5
99.3
94
N.A.
91.9
90.5
N.A.
84.5
66.9
78.2
75.7
N.A.
49.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
86.6
20
0
0
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
100
33.3
13.3
13.3
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.4
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.1
48.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
39
0
0
0
0
0
0
8
8
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
8
8
0
0
0
0
0
0
16
% D
% Glu:
70
0
0
8
8
0
8
0
0
0
0
0
54
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
0
8
8
8
0
0
70
0
0
0
0
% G
% His:
0
16
0
0
8
0
0
8
0
0
0
8
0
0
0
% H
% Ile:
8
0
0
8
0
0
0
0
8
0
0
8
8
8
16
% I
% Lys:
0
0
8
0
16
16
62
0
0
0
0
0
8
0
0
% K
% Leu:
8
0
8
8
0
0
0
0
70
39
0
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
16
8
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
8
0
0
0
8
0
% N
% Pro:
8
0
8
16
0
54
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
70
0
8
0
0
0
0
0
8
16
16
8
0
0
% Q
% Arg:
0
0
8
0
47
0
0
0
0
8
8
54
8
16
0
% R
% Ser:
0
0
16
0
8
0
8
0
0
0
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
16
8
8
0
0
0
0
0
0
54
% T
% Val:
0
0
0
54
8
8
0
0
0
16
0
8
0
54
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
62
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _